The FAv Foundation

FAv Foundation is a registered charity that funds research in Canada into an effective treatment and ultimately a cure for Fanconi Anemia.


Fanconi anemia (FA) is an inherited DNA-repair disease that may lead to bone marrow failure (aplastic anemia), leukemia, and/or solid tumors. It is primarily a recessive disorder: if both parents carry a defect (mutation) in the same FA gene, each of their children has a 25% chance of inheriting the defective gene from both parents. When this happens, the child will have FA.

Scientists have now discovered 23 FA or FA-like genes. FA occurs equally in males and females. It is found in all ethnic groups. Research has added years to the lives of people with FA. Decades ago, children rarely survived to adulthood. Now, there are adults with FA that live into their 30s and beyond.

FA can affect all systems of the body. Many people with FA eventually develop acute myeloid leukemia (AML). FA patients are extremely likely to develop a variety of cancers and at a much earlier age than patients in the general population. Patients who have had a successful bone marrow transplant and are therefore cured of the blood problem associated with FA still must have regular examinations to watch for signs of cancer.


Currently there are over 1000 Canadian’s in need of a bone marrow transplant and DO NOT have a match.  Maybe YOU are someONEs life-saving match?  Want to help?

 If you are a Canadian between the ages of 17-35 you can go online and order your own mouth swabbing kit at One Match – Canada’s Stem Cell and Marrow Network.  (If you are from another country please register with your National Registry)

Stay tuned for our next Life Saving One Match Drive.